Recellcl'in®

Organic passiflora is cultivated in southwestern France, in regions with favorable climate and soil conditions that support healthy plant growth. This climbing plant is grown using sustainable, organic farming practices that prioritize biodiversity, soil health, and manual weed control. Harvesting is carefully timed during peak flowering to preserve botanical quality. The sourcing reflects a commitment to environmental responsibility, old expertise, and a transparent supply chain, delivering an authentic natural ingredient, perfectly suited for cosmetic formulations.

Proprietary preclinical studies

-Re-activation of autophagy system in disturbed sebocytes (in vitro):
An in vitro study was conducted on human sebocytes treated with Recellcl’in® and the androgen hormone DHT to induce sebum overproduction. After 7 days of incubation, the quantification of a key marker of autophagy, was performed using immunostaining and image analysis. Results showed that Recellcl’In® effectively reactivates the autophagy system in sebocytes in a dose-dependent manner, helping to restore cellular balance and, as a result, regulate hyperseborrhea.

-Regulation of sebum production (in vitro):
An in vitro study was conducted on human sebocytes treated with Recellcl’in® and the androgen hormone DHT to induce sebum overproduction. After 7 days of treatment, lipid droplet quantification was performed using immunostaining and image analysis and confirmed the dose-dependent ability of Recellcl’In® to regulate hyperseborrhea in oily and acne-prone skin, correlating with its capacity to restore the autophagy system in disrupted sebocytes.

Clinical study

A randomized, double-blind, placebo-controlled trial was carried out on 33 women with oily or acne-prone skin, who applied a cream containing 2% Recellcl’In® to one side of the face and a placebo to the other, twice daily for 28 days. Results showed that Recellcl’In® effectively rebalances oily skin by significantly reducing sebum production, delivers mattifying benefits by noticeably diminishing skin shininess, refines skin texture, and visibly clarifies the complexion through a marked reduction in pore visibility.

Recommended dose

1 to 2%

Claims

• Re-activation of autophagy system in disturbed sebocytes
• Regulation of sebum production
• Prevention of sebum oxidation
• Reduction of inflammation and enzymatic oxidation: soothing effect

Application

• Oily and acne-prone skin care
• Mattifying and seboregulator skin care
• Pore minimizer

After 28 days of using a cream containing 2% Recellcl’in® :

– 3 out of 4 women agreed that the cream containing Recellcl’in® “makes the skin more radiant and brighter.”
– 91% agreed that the cream containing Recellcl’in® “makes the skin soft.”
– 8 out of 10 women agreed that the cream containing Recellcl’in® “reduces the sticky feeling” and “reduces the sensation of oily skin.